Skip to content
Updated

Level of evidence:

Frequently asked questions about pregnancy hormones

How soon will a pregnancy test be positive?

The pregnancy hormone (hCG) appears 6 to 12 days after ovulation, most often 8 to 10 days, when the embryo implants (Wilcox, 1999). Urine tests are reliable mainly from the day the period is due. Early in a pregnancy that is progressing well, hCG rises by at least 53% in 2 days, and usually much more (Barnhart, 2004).

When is hCG at its highest?

Around 8 to 10 weeks after the last period, then it falls and levels off (Cole, 2010). Nausea is often strongest just after this peak, between 10 and 16 weeks, and usually goes away after 20 weeks (Lee and Saha, 2011).

Why is progesterone essential in early pregnancy?

It keeps the lining of the uterus in place and calms its contractions. In the first weeks, it comes from the corpus luteum of the ovary; around 7 to 9 weeks, the placenta takes over: removing the corpus luteum before then ends the pregnancy, but not after (Csapo, 1972).

Why does blood volume increase during pregnancy?

To supply the placenta: plasma volume rises by about 45% by the end of pregnancy, faster than red blood cells, which dilutes the blood a little (de Haas, 2017).